The Diazyme Small Dense Low-Density Lipoprotein Cholesterol (sdLDL) Assay is a homogeneous enzymatic assay for use in the quantitative determination of sdLDL in human serum. Diazyme's sdLDL test is a homogenous, direct assay for the fast and easy quantification of sdLDL cholesterol.
| Description | Catalog Number | Packaging |
|---|---|---|
| Small Dense Low-Density Lipoprotein-Cholesterol (sdLDL) Assay | DZ560A | R1: 1 x 46 mL R2: 1 x 18.8 mL |
| sdLDL Calibrator Set | DZ560A-CAL | Cal: 1 x 2 mL |
| HDL3/sdLDL Control Set | DZ560A-CON | Con: 1 x 2 mL |
Background
The Diazyme Small Dense Low-Density Lipoprotein Cholesterol (sdLDL) Assay is a homogeneous enzymatic assay for use in the quantitative determination of sdLDL in human serum. Diazyme's sdLDL test is a homogenous, direct assay for the fast and easy quantification of sdLDL cholesterol. It facilitates the fully automated measurement of sdLDL.
Studies found that small, dense LDL, compared to the normal LDL, is more strongly associated with the development of CHD. Determination of sdLDL by ultracentrifugation, electrophoresis-based, or nuclear magnetic resonance methods are laborious and time-consuming.1-2
Downloads
Assay Features
- Homogenous enzymatic assay
- Low limit of quantitation: 2.2 mg/dL
- Improves laboratory efficiency and workflow
- Fast test results (10 minutes) for a rapid turnaround time
- Liquid stable format requires no reagent preparation
- Wide range of instrument parameters available for simplifying implementation
References
- Koba S, Hirano T, Ito Y, Tsunoda R, Yokota Y, Ban Y, Iso Y, Suzuki H, Katagiri T. Significance of small dense low-density lipoprotein-cholesterol concentrations in relation to the severity of coronary heart disease. Atherosclerosis 2006; 189:206-214.
- Hirano T, Ito Y, Saegusa H, Yoshino G. A novel and simple method for quantification of small, dense LDL. J Lipid Res 2003; 44:2193-2201.
Intended use
The sdLDL Assay is a homogeneous enzymatic assay intended for use in the quantitative determination of sdLDL in human serum. The assay is designed for use with chemistry analyzers. For Research Use Only in USA. Not for use in diagnostic procedures.