| Lithium (Enzymatic) Assay (Liquid Stable) | |||
Request package insert information MSDSBrochure |
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| Product Features Compared to existing methods, the new liquid stable Diazyme lithium assay provides improved reagent stability and a dramatically reduced cost per test. The assay features excellent accuracy and precision and offers an extended reportable range of 0.1-3.0 mmole/L lithium which will reduce the need for re-testing elevated patient samples. The method also demonstrates insignificant bias from indigenous ions and other interfering substances including hemoglobin, bilirubin, triglycerides and ascorbic acid. The assay can be applied to most common clinical chemistry analyzers, and application parameters are available from Diazyme. |
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 Assay PrincipleThe Diazyme enzymatic Lithium assay is based on a lithium sensitive enzyme whose activity is lithium concentration dependent. The enzyme, a phosphatase, converts its substrate adenosine biphosphate (PAP) to hypoxanthine through a coupled enzymatic reactions to generate uric acid and hydrogen peroxide (H2O2). H2O2 generated is then quantified by a Trinder reaction. |
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| Intended use The Diazyme Lithium Enzymatic Assay kit is for quantitative in vitro determination of lithium in human serum. Measurements of Lithium are carried out essentially to ensure that proper drug dosage is administered in the treatment of patient suffering from bipolar disorder and to avoid toxicity. |
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| Product | Catalog Number | Packaging | Method/Format |
| Kit (200 Tests) | DZ116B-K | R1: 2 x 20 mL R2: 2 x 10 mL |
Enzymatic/Kinetic Liquid stable |
| Calibrator | DZ116B-Cal | 3 x 3 mL | |
| Control | DZ116B-Con | 2 x 3 mL | |
