| Lithium (Enzymatic) Assay (Liquid Stable) | |||
Request package insert information MSDSBrochure |
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| Product Features Diazyme’s enzymatic lithium assay provides a convenient, stable, non-caustic low cost alternative to expensive ISE and highly caustic alkaline lithium methods. Diazyme’s enzymatic lithium assay demonstrates an excellent correlation with ISE methods and offers excellent precision (%CV <5%) and demonstrates no significant interference from all tested endogenous ions as well as ascorbic acid (5.0 mM), triglycerides (250 mg/dL), and bilirubin (45 mg/dL). |
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 Assay PrincipleThe Diazyme enzymatic Lithium assay is based on a lithium sensitive enzyme whose activity is lithium concentration dependent. The enzyme, a phosphatase, converts its substrate adenosine biphosphate (PAP) to hypoxanthine through a coupled enzymatic reactions to generate uric acid and hydrogen peroxide (H2O2). H2O2 generated is then quantified by a Trinder reaction. |
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| Intended use The Diazyme Lithium Enzymatic Assay kit is for quantitative in vitro determination of lithium in human serum. Measurements of Lithium are carried out essentially to ensure that proper drug dosage is administered in the treatment of patient suffering from bipolar disorder and to avoid toxicity. |
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| Product | Catalog Number | Packaging | Method/Format |
| Kit (200 Tests) | DZ116B-K | R1: 2 x 20 mL R2: 2 x 10 mL |
Enzymatic/Kinetic Liquid stable |
| Calibrator | DZ116B-Cal | 3 x 3 mL | |
| Control | DZ116B-Con | 2 x 3 mL | |
